SLC25A32

Across TCGA patient cohorts, SLC25A32 mutation is significantly associated with the total protein of many other genes, with 13 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC25A32-associated genes across cancer lineages are Cyclin-E2, ACC1, and Ku80. Each is linked with SLC25A32 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC25A32-to-partner and partner-to-SLC25A32 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cyclin-E2 grouped by SLC25A32-low versus SLC25A32-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A32→partner) and Y-score (partner→SLC25A32) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Cyclin-E2 →	+0.186	+2.321	.028	.035	3	2
UCEC	ACC1 →	+0.432	+2.321	.018	.035	3	1
UCEC	Ku80 →	+0.350	+3.472	.003	.002	3	1
UCEC	p62 Lck ligand →	+0.525	+3.459	.001	.005	3	1
UCEC	14-3-3_epsilon →	+0.108	+3.009	.030	.019	3	1
UCEC	p90 RSK →	+0.208	+2.999	.030	.035	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

Cyclin-E2 by SLC25A32 expression — UCEC

Explore this box plot interactively →