SLC25A32

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SLC25A32 mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC25A32-associated genes across cancer lineages are OR10V1, MAGEB4, and CRISP1. Each is linked with SLC25A32 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC25A32-to-partner and partner-to-SLC25A32 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10V1 grouped by SLC25A32-low versus SLC25A32-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A32→partner) and Y-score (partner→SLC25A32) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKINOR10V1 →+0.026+6.022<.001.00131
LARGE_INTESTINEMAGEB4 →+0.022+4.415<.001.00731
LARGE_INTESTINECRISP1 →+0.014+4.415<.001.00731
LARGE_INTESTINESTRA8 →+0.161+4.415<.001.00731
LARGE_INTESTINEC8A →+0.033+4.684<.001.00231
LARGE_INTESTINES100G →+2.043+4.273<.001.00631
Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

OR10V1 by SLC25A32 expression — SKIN

Box plot of OR10V1 in SLC25A32-low vs SLC25A32-high samples in SKIN.

Explore this box plot interactively →

Exploration