SLC25A26

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SLC25A26 mutation is significantly associated with the RNA expression of many other genes, with 514 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC25A26-associated genes across cancer lineages are RPL32P36, NDUFS5P5, and MIR147A. Each is linked with SLC25A26 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC25A26-to-partner and partner-to-SLC25A26 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPL32P36 grouped by SLC25A26-low versus SLC25A26-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A26→partner) and Y-score (partner→SLC25A26) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRPL32P36 →+0.138+2.670.007.00232
UCECNDUFS5P5 →+0.205+2.478<.001.00732
COADMIR147A →+0.617+4.893<.001.00531
COADTRGJP1 →+0.786+4.754.003.00331
COADTRAJ40 →+1.155+4.792<.001.00331
COADRPL5P31 →+0.206+4.446.001.00631
Each partner links to its Q-omics profile. Showing the 6 strongest of 514 associations by consensus.

RPL32P36 by SLC25A26 expression — UCEC

Box plot of RPL32P36 in SLC25A26-low vs SLC25A26-high samples in UCEC.

Explore this box plot interactively →

Exploration