SLC25A25

Across TCGA patient cohorts, SLC25A25 mutation is significantly associated with the RNA expression of many other genes, with 2,614 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC25A25-associated genes across cancer lineages are OR5AW1P, TUBB4BP1, and RNU6-628P. Each is linked with SLC25A25 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC25A25-to-partner and partner-to-SLC25A25 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR5AW1P grouped by SLC25A25-low versus SLC25A25-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A25→partner) and Y-score (partner→SLC25A25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	OR5AW1P →	+0.092	+4.970	<.001	.005	3	2
LUSC	TUBB4BP1 →	+0.139	+4.853	.001	.004	3	2
BLCA	RNU6-628P →	+0.421	+3.854	.007	.004	3	2
SKCM	SUMO2P5 →	+0.136	+5.469	<.001	.002	3	2
SKCM	MLLT10P2 →	+0.176	+5.469	<.001	.002	3	2
COAD	TRMT112P1 →	+0.118	+6.153	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,614 associations by consensus.

OR5AW1P by SLC25A25 expression — SKCM

Explore this box plot interactively →