SLC25A25

Across TCGA cell cohorts, SLC25A25 mutation is significantly associated with the RNA expression of many other genes, with 37 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC25A25-associated genes across cancer lineages are DUSP29, MTRNR2L7, and OR13C2. Each is linked with SLC25A25 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC25A25-to-partner and partner-to-SLC25A25 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DUSP29 grouped by SLC25A25-low versus SLC25A25-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A25→partner) and Y-score (partner→SLC25A25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	DUSP29 →	+0.440	+4.781	<.001	.003	3	1
BREAST	MTRNR2L7 →	+0.032	+4.421	<.001	.004	3	1
BREAST	OR13C2 →	+0.026	+5.312	<.001	<.001	3	1
BREAST	OR4E1 →	+0.112	+4.781	<.001	.003	3	1
BLOOD_Leukemia	CCKBR →	+0.603	+3.864	.001	.003	3	1
BLOOD_Leukemia	C9 →	+1.181	+3.775	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 37 associations by consensus.

DUSP29 by SLC25A25 expression — BREAST

Explore this box plot interactively →