SLC25A25-AS1

Across TCGA pan-cancer cohorts, SLC25A25-AS1 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated SLC25A25-AS1 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher SLC25A25-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated SLC25A25-AS1 expression acts as an unfavorable survival marker, although some lineages such as BLCA and SKCM show a favorable association.

ACC, KIRC, and BLCA are the cancer types where SLC25A25-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Median	All	0.369	0.792	<.001	101	view →
KIRC	DFS	Median	III,IV	0.348	0.559	.002	72	view →
BLCA	OS	Median	All	0.686	0.534	<.001	64	view →
SKCM	DFS	Tertile	All	0.706	0.520	.001	56	view →
COAD	OS	Median	All	0.825	0.909	<.001	48	view →
HNSC	OS	Tertile	II,III,IV	0.825	0.713	.026	22	view →
PRAD	DFS	Median	All	0.819	0.943	<.001	22	view →
UVM	DFS	Tertile	All	0.279	0.896	.020	12	view →
MESO	DFS	Tertile	IV	0.140	0.743	.001	12	view →
PAAD	DFS	Quartile	All	0.437	0.160	.018	12	view →
ESCA	OS	Median	All	0.617	1.000	.009	9	view →
THYM	OS	Median	II,III,IV	1.000	0.746	.029	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

SLC25A25-AS1–ACC (DFS)

Open the ACC breakdown →