SLC25A25-AS1

Across TCGA pan-cancer cohorts, SLC25A25-AS1 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of SLC25A25-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where SLC25A25-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types SLC25A25-AS1 is over-expressed in tumor, although a few such as KIRC and KIRP show the opposite, repressed pattern.

KIRC, KIRP, and CHOL are the cancer types where SLC25A25-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SLC25A25-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Female	IV	−1.773	<.001	12	view →
KIRP	All	All	−1.031	<.001	7	view →
CHOL	All	All	+1.794	<.001	5	view →
HNSC	Female	IV	−1.308	.003	5	view →
STAD	All	All	+0.940	<.001	4	view →
LIHC	Female	All	+0.809	<.001	4	view →
COAD	Female	All	−0.502	.006	4	view →
LUSC	All	All	+0.487	.002	4	view →
PAAD	Male	All	+0.950	.004	2	view →
UCEC	All	All	+0.482	.049	2	view →
LUAD	All	All	+0.383	.006	2	view →
READ	Female	All	+1.276	.008	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

SLC25A25-AS1–KIRC

Open the KIRC breakdown →