SLC25A23

Across TCGA pan-cancer cohorts, SLC25A23 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated SLC25A23 data layer compared with 24 for mass-spec protein and 2 for mass-spec protein.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher SLC25A23 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated SLC25A23 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

LUAD, UCEC, and COAD are the cancer types where SLC25A23 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	All	0.307	0.687	.001	27	view →
UCEC	DFS	Median	All	1.000	0.622	.013	20	view →
COAD	OS	Median	III,IV	0.191	0.786	<.001	17	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

SLC25A23–LUAD (OS)

Open the LUAD breakdown →