SLC25A23

Across TCGA patient cohorts, SLC25A23 mutation is significantly associated with the RNA expression of many other genes, with 2,732 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC25A23-associated genes across cancer lineages are FKBP4P7, S100A11P10, and CCL4. Each is linked with SLC25A23 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC25A23-to-partner and partner-to-SLC25A23 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FKBP4P7 grouped by SLC25A23-low versus SLC25A23-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A23→partner) and Y-score (partner→SLC25A23) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	FKBP4P7 →	+0.032	+3.962	<.001	.005	3	2
STAD	S100A11P10 →	+0.124	+5.070	<.001	.004	3	2
UCEC	CCL4 →	+0.679	+2.191	.009	.002	3	2
UCEC	TUBGCP5 →	+0.450	+2.202	.001	.001	3	2
UCEC	POLDIP3 →	+0.418	+2.847	.007	.001	3	2
UCEC	PPP4R3A →	+0.493	+3.708	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,732 associations by consensus.

FKBP4P7 by SLC25A23 expression — LUAD

Explore this box plot interactively →