SLC25A23

Across TCGA patient cohorts, SLC25A23 mutation is significantly associated with the total protein of many other genes, with 35 significant associations in total. COAD shows the largest number of these associations.

The most reproducible SLC25A23-associated genes across cancer lineages are Bak, FASN, and FoxM1. Each is linked with SLC25A23 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC25A23-to-partner and partner-to-SLC25A23 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Bak grouped by SLC25A23-low versus SLC25A23-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A23→partner) and Y-score (partner→SLC25A23) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Bak →	+0.206	+2.459	.040	.018	3	3
UCEC	FASN →	+0.339	+1.906	.032	.016	3	2
UCEC	FoxM1 →	+0.277	+2.415	.007	.003	3	2
UCEC	STAT3_pY705 →	-0.445	-2.222	<.001	.009	3	2
UCEC	Cyclin-B1 →	+0.669	+2.415	.003	.003	3	2
COAD	c-Kit →	-0.740	-3.000	.008	.035	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 35 associations by consensus.

Bak by SLC25A23 expression — UCEC

Explore this box plot interactively →