SLC25A23

Across TCGA cell cohorts, SLC25A23 mutation is significantly associated with the RNA expression of many other genes, with 16 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC25A23-associated genes across cancer lineages are KRTAP5-6, C20orf85, and IL22. Each is linked with SLC25A23 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC25A23-to-partner and partner-to-SLC25A23 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KRTAP5-6 grouped by SLC25A23-low versus SLC25A23-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A23→partner) and Y-score (partner→SLC25A23) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	KRTAP5-6 →	+0.126	+4.022	<.001	.001	3	1
BLOOD_Leukemia	C20orf85 →	+0.049	+5.969	<.001	.001	3	1
BLOOD_Leukemia	IL22 →	+0.050	+6.569	<.001	<.001	3	1
BLOOD_Leukemia	LYZL2 →	+0.033	+6.569	<.001	<.001	3	1
BLOOD_Leukemia	SPHKAP →	+0.012	+4.922	<.001	.009	3	1
BLOOD_Leukemia	KRT24 →	+0.096	+5.201	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

KRTAP5-6 by SLC25A23 expression — OVARY

Explore this box plot interactively →