SLC25A21-AS1

Across TCGA pan-cancer cohorts, SLC25A21-AS1 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated SLC25A21-AS1 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher SLC25A21-AS1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated SLC25A21-AS1 expression acts as an unfavorable survival marker, although some lineages such as UVM and LGG show a favorable association.

UVM, STAD, and LGG are the cancer types where SLC25A21-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	DFS	Tertile	All	0.846	0.397	<.001	97	view →
STAD	DFS	Tertile	All	0.248	0.523	.001	85	view →
LGG	OS	Median	All	0.870	0.744	<.001	45	view →
KIRP	OS	Median	II,III,IV	0.711	0.363	<.001	42	view →
PAAD	DFS	Median	II,III,IV	0.526	0.372	.001	39	view →
UCS	DFS	Tertile	II,III,IV	0.576	0.132	.002	36	view →
BRCA	OS	Tertile	III,IV	0.959	0.823	<.001	32	view →
MESO	OS	Median	All	0.728	0.294	.004	27	view →
KIRC	OS	Quartile	All	0.848	0.724	.002	26	view →
OV	DFS	Quartile	IV	0.573	0.324	.017	22	view →
ESCA	OS	Tertile	All	1.000	0.516	.014	21	view →
ACC	DFS	Quartile	IV	0.695	0.080	.006	20	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

SLC25A21-AS1–UVM (DFS)

Open the UVM breakdown →