SLC25A21-AS1

Across TCGA pan-cancer cohorts, SLC25A21-AS1 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of SLC25A21-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where SLC25A21-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types SLC25A21-AS1 is over-expressed in tumor, although a few such as KIRC and LUAD show the opposite, repressed pattern.

KIRC, LUAD, and UCEC are the cancer types where SLC25A21-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SLC25A21-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	II,III,IV	−0.783	<.001	7	view →
LUAD	Female	II,III,IV	−0.684	<.001	7	view →
UCEC	All	III,IV	−1.567	<.001	6	view →
LUSC	Male	III,IV	−1.537	<.001	6	view →
KICH	All	All	−1.308	<.001	6	view →
BRCA	Female	All	−0.699	<.001	6	view →
LIHC	All	All	+0.413	<.001	6	view →
READ	All	All	−1.215	<.001	5	view →
CHOL	All	All	+1.105	<.001	5	view →
THCA	Male	All	−0.398	.015	5	view →
STAD	All	All	−0.571	.005	4	view →
COAD	All	II,III,IV	−0.332	.020	3	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

SLC25A21-AS1–KIRC

Open the KIRC breakdown →