SLC25A19

Across TCGA patient cohorts, SLC25A19 mutation is significantly associated with the RNA expression of many other genes, with 850 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC25A19-associated genes across cancer lineages are RNU6-492P, RNU4-26P, and RN7SKP39. Each is linked with SLC25A19 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC25A19-to-partner and partner-to-SLC25A19 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-492P grouped by SLC25A19-low versus SLC25A19-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A19→partner) and Y-score (partner→SLC25A19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RNU6-492P →	+0.478	+7.954	<.001	.008	3	1
HNSC	RNU4-26P →	+0.268	+7.954	<.001	.008	3	1
BLCA	RN7SKP39 →	+0.132	+5.177	<.001	.007	3	1
BLCA	RN7SKP89 →	+0.230	+5.177	<.001	.007	3	1
BLCA	RPL30P1 →	+0.114	+5.685	<.001	.003	3	1
BLCA	ZNF25-DT →	+0.096	+5.329	.002	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 850 associations by consensus.

RNU6-492P by SLC25A19 expression — HNSC

Explore this box plot interactively →