SLC25A19

Across TCGA cell cohorts, SLC25A19 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC25A19-associated genes across cancer lineages are OR1D2, OR13G1, and IL31. Each is linked with SLC25A19 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC25A19-to-partner and partner-to-SLC25A19 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR1D2 grouped by SLC25A19-low versus SLC25A19-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A19→partner) and Y-score (partner→SLC25A19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	OR1D2 →	+0.017	+5.022	<.001	.002	3	1
LARGE_INTESTINE	OR13G1 →	+0.024	+4.415	<.001	.007	3	1
LARGE_INTESTINE	IL31 →	+0.033	+4.273	<.001	.006	3	1
BLOOD_Leukemia	GHRHR →	+0.467	+4.705	<.001	.003	3	1
BLOOD_Leukemia	TCF21 →	+0.019	+4.705	<.001	.003	3	1
BLOOD_Leukemia	NXPE4 →	+0.020	+4.276	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

OR1D2 by SLC25A19 expression — LARGE_INTESTINE

Explore this box plot interactively →