SLC25A18

Across TCGA patient cohorts, SLC25A18 mutation is significantly associated with the RNA expression of many other genes, with 1,022 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC25A18-associated genes across cancer lineages are OR5D3P, HMGN2P32, and CALM1P1. Each is linked with SLC25A18 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC25A18-to-partner and partner-to-SLC25A18 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR5D3P grouped by SLC25A18-low versus SLC25A18-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A18→partner) and Y-score (partner→SLC25A18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	OR5D3P →	+0.046	+4.595	.004	.004	3	2
COAD	HMGN2P32 →	+0.932	+3.852	<.001	.003	3	2
COAD	CALM1P1 →	+0.693	+3.795	<.001	.003	3	2
COAD	RANP5 →	+0.270	+3.541	<.001	.002	3	2
COAD	UBE3AP2 →	+0.100	+4.258	.005	<.001	3	2
COAD	ASS1P8 →	+0.416	+3.896	.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,022 associations by consensus.

OR5D3P by SLC25A18 expression — COAD

Explore this box plot interactively →