Q-omics provides the consensus-scored RANP5 profile across patient tissues and cancer cell-line models. RANP5 expression is associated with patient survival in 17 of 34 cancer types, with the highest sampling consensus in KIRC. Among the 18 cancer types available for tumor–normal comparison, RANP5 is differentially expressed in 3, with the highest sampling consensus in HNSC. Additionally, RANP5 RNA expression shows 6,276 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight KIRC, HNSC, and STAD as cancer lineages where RANP5 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for RANP5 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes RANP5 survival associations across molecular data types. RANP5 RNA expression shows survival associations in the most cancer types (17). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible RANP5 RNA expression–survival associations across cancer types. High RANP5 expression shows unfavorable associations in KIRC, ACC, LGG and UVM, but favorable associations in OV and UCS. The KIRC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify KIRC as the clearest survival context for RANP5 RNA expression.
This table summarizes RANP5 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 3. The strongest signals are observed in HNSC for RNA.
This table ranks reproducible tumor–normal expression differences for RANP5. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. RANP5 shows lower tumor expression in PAAD and higher tumor expression in HNSC and COAD. The HNSC box plot shows higher RANP5 RNA expression in tumor versus normal tissue (log2 FC = +0.078, t-test p < 0.001).
This table shows molecular features associated with RANP5 in patient tissues and cancer cell lines. In patient samples, RANP5 shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.
