SLC25A17

Across TCGA patient cohorts, SLC25A17 mutation is significantly associated with the RNA expression of many other genes, with 1,068 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC25A17-associated genes across cancer lineages are AAGAB, ZWINT, and PHAX. Each is linked with SLC25A17 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC25A17-to-partner and partner-to-SLC25A17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AAGAB grouped by SLC25A17-low versus SLC25A17-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A17→partner) and Y-score (partner→SLC25A17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	AAGAB →	+0.527	+2.265	.001	.006	3	2
UCEC	ZWINT →	+0.663	+3.251	.008	.008	3	2
UCEC	PHAX →	+0.444	+3.362	.005	.005	3	2
UCEC	AKIP1 →	+0.423	+3.346	.006	.005	3	2
UCEC	FAM118B →	+0.539	+3.234	.002	.008	3	2
UCEC	TAF9 →	+0.775	+3.700	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,068 associations by consensus.

AAGAB by SLC25A17 expression — UCEC

Explore this box plot interactively →