SLC25A17

Across TCGA cell cohorts, SLC25A17 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,467 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SLC25A17-associated GO terms across cancer lineages are DNA replication checkpoint signaling, Regulation of chromosome condensation, and DNA replication. Each is linked with SLC25A17 in more than 15 cancer types. Because this analysis shows association rather than direction, both SLC25A17-to-partner and partner-to-SLC25A17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA replication checkpoint signaling grouped by SLC25A17-low versus SLC25A17-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A17→partner) and Y-score (partner→SLC25A17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	DNA replication checkpoint signaling →	+0.144	+0.672	<.001	.001	3	15
UPPER_AERODIGESTIVE_TRACT	Regulation of chromosome condensation →	+0.160	+0.746	.001	<.001	3	15
OESOPHAGUS	DNA replication →	+0.124	+0.711	.003	.006	2	16
UPPER_AERODIGESTIVE_TRACT	DNA replication initiation →	+0.184	+0.859	<.001	<.001	3	15
OESOPHAGUS	DNA-templated DNA replication →	+0.136	+0.711	.001	.006	2	15
BLOOD_Myeloma	Spindle elongation →	+0.225	+0.845	.002	.009	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,467 associations by consensus.

DNA replication checkpoint signaling by SLC25A17 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →