SLC25A17

Across TCGA cell cohorts, SLC25A17 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. URINARY_TRACT shows the largest number of these associations.

The most reproducible SLC25A17-associated genes across cancer lineages are PPP1R2C, CES5A, and MPC1L. Each is linked with SLC25A17 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC25A17-to-partner and partner-to-SLC25A17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PPP1R2C grouped by SLC25A17-low versus SLC25A17-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A17→partner) and Y-score (partner→SLC25A17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	PPP1R2C →	+0.230	+4.539	<.001	.007	3	2
URINARY_TRACT	CES5A →	+0.012	+4.087	<.001	.009	3	1
URINARY_TRACT	MPC1L →	+0.062	+4.087	<.001	.009	3	1
URINARY_TRACT	PCDH11Y →	+0.012	+4.087	<.001	.009	3	1
BLOOD_Leukemia	CST8 →	+0.046	+4.969	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

PPP1R2C by SLC25A17 expression — BLOOD_Leukemia

Explore this box plot interactively →