SLC25A17

mutation — cross-omics
Cross-omicsMUTATION → MUTATIONCell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SLC25A17 mutation is significantly associated with the mutation status of many other genes, with 1,568 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC25A17-associated genes across cancer lineages are CDH23, TCERG1, and PGAP6. Each is linked with SLC25A17 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC25A17-to-partner and partner-to-SLC25A17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CDH23 grouped by SLC25A17-low versus SLC25A17-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A17→partner) and Y-score (partner→SLC25A17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaCDH23 →+2.202+3.442.002.00213
OVARYTCERG1 →+4.415+4.977.007.00713
BLOOD_LeukemiaPGAP6 →+3.050+3.247.008.00813
BLOOD_LeukemiaXPO7 →+3.313+3.430.005.00513
BLOOD_LeukemiaPRUNE1 →+5.050+4.000.008.00813
OVARYTMEM94 →+4.415+4.977.007.00713
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,568 associations by consensus.

CDH23 by SLC25A17 expression — BLOOD_Leukemia

Box plot of CDH23 in SLC25A17-low vs SLC25A17-high samples in BLOOD_Leukemia.

Explore this box plot interactively →

Exploration