SLC25A16

Across TCGA cell cohorts, SLC25A16 mutation is significantly associated with the RNA expression of many other genes, with 17 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC25A16-associated genes across cancer lineages are CST8, LHCGR, and VCX2. Each is linked with SLC25A16 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC25A16-to-partner and partner-to-SLC25A16 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CST8 grouped by SLC25A16-low versus SLC25A16-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A16→partner) and Y-score (partner→SLC25A16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CST8 →	+0.021	+4.415	<.001	.007	3	1
LARGE_INTESTINE	LHCGR →	+0.063	+4.467	<.001	.004	3	1
LARGE_INTESTINE	VCX2 →	+1.507	+4.415	<.001	.007	3	1
LARGE_INTESTINE	FIGLA →	+0.037	+4.415	<.001	.007	3	1
LARGE_INTESTINE	DEFB132 →	+0.074	+4.415	<.001	.007	3	1
LARGE_INTESTINE	FAM205C →	+0.015	+5.022	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

CST8 by SLC25A16 expression — LARGE_INTESTINE

Explore this box plot interactively →