SLC25A15

Across TCGA pan-cancer cohorts, SLC25A15 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated SLC25A15 data layer compared with 23 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher SLC25A15 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated SLC25A15 expression acts as an unfavorable survival marker, although some lineages such as LUAD and CCRCC show a favorable association.

LUAD, LSCC, and UCEC are the cancer types where SLC25A15 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Median	III,IV	0.783	0.269	.003	27	view →
LSCC	DFS	Median	All	0.528	0.919	.013	12	view →
UCEC	DFS	Tertile	All	0.760	0.944	.021	8	view →
PDAC	DFS	Median	IV	0.245	0.715	.038	3	view →
CCRCC	DFS	Tertile	All	0.982	0.547	.011	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

SLC25A15–LUAD (DFS)

Open the LUAD breakdown →