SLC25A15

Across TCGA patient cohorts, SLC25A15 mutation is significantly associated with the RNA expression of many other genes, with 1,751 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC25A15-associated genes across cancer lineages are INCENP, CPSF7, and YTHDF1. Each is linked with SLC25A15 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC25A15-to-partner and partner-to-SLC25A15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, INCENP grouped by SLC25A15-low versus SLC25A15-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A15→partner) and Y-score (partner→SLC25A15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	INCENP →	+0.785	+3.850	.002	<.001	3	1
UCEC	CPSF7 →	+0.465	+3.354	.001	.005	3	1
UCEC	YTHDF1 →	+0.401	+2.732	.001	.003	3	1
UCEC	FCGR1A →	+0.629	+3.346	.007	.005	3	1
UCEC	TIRAP →	+0.571	+3.483	.001	.002	3	1
UCEC	MTMR12 →	+0.735	+3.807	.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,751 associations by consensus.

INCENP by SLC25A15 expression — UCEC

Explore this box plot interactively →