SLC25A15

Across TCGA patient cohorts, SLC25A15 mutation is significantly associated with the total protein of many other genes, with 12 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC25A15-associated genes across cancer lineages are eIF4G, FOXO3a_pS318_S321, and NDRG1_pT346. Each is linked with SLC25A15 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC25A15-to-partner and partner-to-SLC25A15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eIF4G grouped by SLC25A15-low versus SLC25A15-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A15→partner) and Y-score (partner→SLC25A15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eIF4G →	+0.436	+2.321	.005	.035	3	1
UCEC	FOXO3a_pS318_S321 →	-0.160	-3.160	.010	.019	3	1
UCEC	NDRG1_pT346 →	-0.533	-2.321	.030	.035	3	1
UCEC	PDCD4 →	-0.747	-3.459	.001	.005	3	1
UCEC	Stathmin →	+0.158	+2.833	.022	.034	3	1
UCEC	YB-1_pS102 →	-0.200	-3.459	.031	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

eIF4G by SLC25A15 expression — UCEC

Explore this box plot interactively →