SLC25A10

Across TCGA pan-cancer cohorts, SLC25A10 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated SLC25A10 data layer compared with 28 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher SLC25A10 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated SLC25A10 expression acts as an unfavorable survival marker, although some lineages such as HNSC and GBM show a favorable association.

HNSC, LUAD, and GBM are the cancer types where SLC25A10 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Quartile	II,III,IV	0.838	0.436	<.001	26	view →
LUAD	DFS	Median	All	0.398	0.898	.001	22	view →
GBM	DFS	Tertile	All	0.891	0.629	.022	2	view →
LSCC	OS	Tertile	All	1.000	0.736	.043	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

SLC25A10–HNSC (DFS)

Open the HNSC breakdown →