SLC25A10

Across TCGA pan-cancer cohorts, SLC25A10 RNA differs between tumor and matched normal tissue in 15 of 18 cancer types tested, making tumor–normal expression one of SLC25A10’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where SLC25A10 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SLC25A10 is over-expressed in tumor, although a few such as KIRC and CHOL show the opposite, repressed pattern.

LUAD, LUSC, and BLCA are the cancer types where SLC25A10 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SLC25A10 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	Female	III,IV	+2.288	<.001	11	view →
LUSC	All	III,IV	+2.306	<.001	8	view →
BLCA	All	All	+1.292	.001	7	view →
STAD	All	All	+1.291	<.001	7	view →
KIRC	Male	All	−0.893	<.001	7	view →
COAD	Female	II,III,IV	+0.732	<.001	7	view →
UCEC	All	All	+2.755	<.001	6	view →
BRCA	All	II,III,IV	+0.634	<.001	6	view →
LIHC	Male	All	+0.665	<.001	4	view →
CHOL	All	All	−0.865	.001	2	view →
PRAD	All	All	+0.853	<.001	2	view →
KICH	All	All	−0.624	.011	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 15 lineages.

SLC25A10–LUAD

Open the LUAD breakdown →