SLC25A10

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SLC25A10 mutation is significantly associated with the RNA expression of many other genes, with 1,177 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC25A10-associated genes across cancer lineages are TRAJ27, GOLGA6L11P, and SRP72P1. Each is linked with SLC25A10 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC25A10-to-partner and partner-to-SLC25A10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRAJ27 grouped by SLC25A10-low versus SLC25A10-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A10→partner) and Y-score (partner→SLC25A10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECTRAJ27 →+1.150+3.323<.001<.00132
UCECGOLGA6L11P →+0.021+4.002<.001.00132
UCECSRP72P1 →+0.162+2.640<.001.00331
UCECMIR5188 →+0.801+2.498<.001.00131
UCECRN7SL605P →+0.481+2.565<.001.00431
UCECMIR3909 →+0.324+2.326.001.00531
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,177 associations by consensus.

TRAJ27 by SLC25A10 expression — UCEC

Box plot of TRAJ27 in SLC25A10-low vs SLC25A10-high samples in UCEC.

Explore this box plot interactively →

Exploration