SLC25A10

Across TCGA patient cohorts, SLC25A10 mutation is significantly associated with the total protein of many other genes, with 13 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC25A10-associated genes across cancer lineages are eIF4E, Lck, and MSH6. Each is linked with SLC25A10 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC25A10-to-partner and partner-to-SLC25A10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eIF4E grouped by SLC25A10-low versus SLC25A10-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A10→partner) and Y-score (partner→SLC25A10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eIF4E →	+0.217	+2.459	.033	.020	3	1
UCEC	Lck →	+0.239	+2.459	.013	.020	3	1
UCEC	MSH6 →	-0.367	-2.990	.021	.036	3	1
UCEC	Notch1 →	+0.184	+2.183	.006	.033	3	1
UCEC	PKC-a_pS657 →	-0.434	-2.990	.018	.036	3	1
UCEC	PRDX1 →	+0.213	+3.321	.032	.010	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

eIF4E by SLC25A10 expression — UCEC

Explore this box plot interactively →