SLC25A10

Across TCGA cell cohorts, SLC25A10 mutation is significantly associated with the RNA expression of many other genes, with 63 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC25A10-associated genes across cancer lineages are CBY1, GALR3, and NARS1. Each is linked with SLC25A10 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC25A10-to-partner and partner-to-SLC25A10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CBY1 grouped by SLC25A10-low versus SLC25A10-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A10→partner) and Y-score (partner→SLC25A10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CBY1 →	+0.828	+3.160	<.001	.006	3	1
LARGE_INTESTINE	GALR3 →	+0.105	+3.424	<.001	.006	3	1
LARGE_INTESTINE	NARS1 →	+0.936	+3.067	.001	.009	3	1
LARGE_INTESTINE	GTF2B →	+0.468	+3.215	.001	.009	3	1
LARGE_INTESTINE	GID4 →	+0.831	+3.067	<.001	.009	3	1
LARGE_INTESTINE	ELAC1 →	+0.697	+3.215	.004	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 63 associations by consensus.

CBY1 by SLC25A10 expression — LARGE_INTESTINE

Explore this box plot interactively →