SLC25A1

Across TCGA patient cohorts, SLC25A1 protein abundance is significantly associated with the RNA expression of many other genes, with 14,162 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SLC25A1-associated genes across cancer lineages are NLRP3, NPR1, and C22orf39. Each is linked with SLC25A1 in more than 4 cancer types. Because this analysis shows association rather than direction, both SLC25A1-to-partner and partner-to-SLC25A1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLC25A1 versus NLRP3 in HNSC, with a Pearson correlation of -0.24.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A1→partner) and Y-score (partner→SLC25A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	NLRP3 →	-0.556	-0.318	.003	.001	3	5
UCEC	NPR1 →	-0.866	-0.505	.006	<.001	3	5
OV	C22orf39 →	+0.546	+0.439	<.001	<.001	3	5
UCEC	GYPC →	-0.644	-0.426	.003	.005	3	5
BRCA	HAPLN3 →	-1.404	-0.705	<.001	<.001	3	5
UCEC	CLIC2 →	-0.679	-0.512	.002	.005	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,162 associations by consensus.

SLC25A1 vs NLRP3 — HNSC

Explore this scatter interactively →