SLC24A2

Across TCGA cell cohorts, SLC24A2 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. OESOPHAGUS shows the largest number of these associations.

The most reproducible SLC24A2-associated genes across cancer lineages are FAM25C, GKN2, and AKAIN1. Each is linked with SLC24A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC24A2-to-partner and partner-to-SLC24A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FAM25C grouped by SLC24A2-low versus SLC24A2-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC24A2→partner) and Y-score (partner→SLC24A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	FAM25C →	+0.856	+4.930	<.001	.001	3	2
OESOPHAGUS	GKN2 →	+0.372	+4.017	.004	.007	3	1
OESOPHAGUS	AKAIN1 →	+0.064	+4.017	<.001	.007	3	1
SKIN	MTNR1B →	+0.055	+4.684	<.001	.002	3	1
LARGE_INTESTINE	GSG1L2 →	+0.011	+3.700	<.001	.009	3	1
LUNG_NSCLC_LUAD	CCDC195 →	+0.034	+4.887	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

FAM25C by SLC24A2 expression — SKIN

Explore this box plot interactively →