SLC24A2

Across TCGA pan-cancer cohorts, SLC24A2 RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated SLC24A2 data layer compared with 7 for mutation status.

The strongest signal is observed in thyroid carcinoma (THCA), where higher SLC24A2 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated SLC24A2 expression acts as an unfavorable survival marker, although some lineages such as LUSC and TGCT show a favorable association.

THCA, STAD, and LIHC are the cancer types where SLC24A2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THCA	DFS	Quartile	All	0.838	0.928	.001	71	view →
STAD	OS	Quartile	All	0.280	0.463	.004	37	view →
LIHC	DFS	Tertile	All	0.395	0.593	.001	26	view →
LUSC	DFS	Median	II,III,IV	0.466	0.262	.004	25	view →
KIRC	DFS	Median	III,IV	0.288	0.543	.010	23	view →
DLBC	OS	Median	II,III,IV	0.286	1.000	.004	15	view →
OV	OS	Quartile	IV	0.316	0.577	.021	14	view →
KIRP	OS	Median	All	0.443	0.807	.005	14	view →
TGCT	DFS	Median	All	0.935	0.726	<.001	14	view →
UVM	OS	Median	III,IV	0.258	0.836	.007	13	view →
READ	DFS	Tertile	IV	0.271	0.755	.016	12	view →
SCLC	OS	Median	IV	0.233	0.718	.015	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

SLC24A2–THCA (DFS)

Open the THCA breakdown →