SLC23A2

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, SLC23A2 mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated SLC23A2 data layer compared with 25 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher SLC23A2 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated SLC23A2 expression acts as an unfavorable survival marker, although some lineages such as LUAD and GBM show a favorable association.

LUAD and GBM are the cancer types where SLC23A2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
LUADDFSMedianIII,IV0.9220.409.0243view →
GBMOSMedianAll0.4880.275.0182view →
Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

SLC23A2–LUAD (DFS)

Kaplan–Meier survival curve for SLC23A2 mass-spec protein-high vs -low samples in LUAD.

Open the LUAD breakdown →

Exploration