SLC23A2

Across TCGA cell cohorts, SLC23A2 mutation is significantly associated with the RNA expression of many other genes, with 178 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC23A2-associated genes across cancer lineages are OR2B2, EDDM3B, and PPP1R2C. Each is linked with SLC23A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC23A2-to-partner and partner-to-SLC23A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR2B2 grouped by SLC23A2-low versus SLC23A2-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC23A2→partner) and Y-score (partner→SLC23A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	OR2B2 →	+0.027	+4.684	<.001	.002	3	1
SKIN	EDDM3B →	+0.029	+4.415	<.001	.007	3	1
BLOOD_Leukemia	PPP1R2C →	+0.240	+4.539	<.001	.007	3	1
BLOOD_Leukemia	GOLGA6L2 →	+0.024	+4.705	<.001	.003	3	1
BLOOD_Leukemia	NPAP1 →	+0.057	+4.551	.004	.004	3	1
BLOOD_Leukemia	SLC36A2 →	+0.028	+4.551	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 178 associations by consensus.

OR2B2 by SLC23A2 expression — SKIN

Explore this box plot interactively →