SLC22A9

Across TCGA cell cohorts, SLC22A9 mutation is significantly associated with the RNA expression of many other genes, with 22 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible SLC22A9-associated genes across cancer lineages are OR10Q1, C16orf82, and CD180. Each is linked with SLC22A9 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC22A9-to-partner and partner-to-SLC22A9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10Q1 grouped by SLC22A9-low versus SLC22A9-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC22A9→partner) and Y-score (partner→SLC22A9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	OR10Q1 →	+0.060	+4.189	<.001	.002	3	2
LUNG_NSCLC_LUAD	C16orf82 →	+0.007	+4.078	<.001	.009	3	2
LUNG_NSCLC_LUAD	CD180 →	+0.327	+3.977	<.001	.005	3	1
LUNG_NSCLC_LUAD	SLC36A2 →	+0.025	+3.760	<.001	.008	3	1
LUNG_NSCLC_LUAD	OPTC →	+0.027	+3.977	<.001	.005	3	1
LUNG_NSCLC_LUAD	SPANXN3 →	+0.423	+3.544	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 22 associations by consensus.

OR10Q1 by SLC22A9 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →