SLC22A8

Across TCGA patient cohorts, SLC22A8 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,924 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SLC22A8-associated proteins across cancer lineages are DNAJC2_S63, NCOA7, and CRYM. Each is linked with SLC22A8 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC22A8-to-partner and partner-to-SLC22A8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLC22A8 versus DNAJC2_S63 in GBM, with a Pearson correlation of -0.44.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC22A8→partner) and Y-score (partner→SLC22A8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	DNAJC2_S63 →	-0.411	-0.159	.002	.003	3	3
GBM	NCOA7 →	+0.558	+0.223	<.001	<.001	3	3
GBM	CRYM →	+0.709	+0.128	<.001	<.001	3	3
GBM	SNX30 →	+0.269	+0.137	<.001	.005	3	3
GBM	RSL1D1 →	-0.378	-0.142	.001	.002	3	3
CCRCC	HSPA12B →	+0.415	+0.440	<.001	.007	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,924 associations by consensus.

SLC22A8 vs DNAJC2_S63 — GBM

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