Across TCGA patient cohorts, SLC22A6 mutation is significantly associated with the RNA expression of many other genes, with 1,833 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC22A6-associated genes across cancer lineages are CENPU, GAPLINC, and EIF4E2P2. Each is linked with SLC22A6 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC22A6-to-partner and partner-to-SLC22A6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC22A6→partner) and Y-score (partner→SLC22A6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CENPU →	+0.697	+3.743	.001	<.001	3	3
UCEC	GAPLINC →	+0.455	+2.807	.003	<.001	3	3
CESC	EIF4E2P2 →	+0.098	+4.450	.006	.002	3	2
CESC	RNU6-797P →	+0.166	+4.559	<.001	.006	3	2
CESC	HSFY1P1 →	+0.014	+4.757	<.001	.004	3	2
UCEC	MIR6870 →	+0.287	+2.174	.002	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,833 associations by consensus.

Exploration

SLC22A6 survival (RNA) · tumor vs normal (RNA) · all SLC22A6 data types