Across TCGA patient cohorts, SLC22A4 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,926 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible SLC22A4-associated proteins across cancer lineages are RPL10A, RPL27, and RPL3. Each is linked with SLC22A4 in more than 3 cancer types. Because this analysis shows association rather than direction, both SLC22A4-to-partner and partner-to-SLC22A4 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC22A4→partner) and Y-score (partner→SLC22A4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RPL10A →	-0.225	-0.899	<.001	<.001	3	4
HNSC	RPL27 →	-0.253	-0.484	<.001	.002	3	4
LSCC	RPL3 →	-0.247	-0.427	<.001	.002	3	4
BRCA	RPL7 →	-0.234	-0.635	.004	.001	3	4
HNSC	RPLP0 →	-0.198	-0.623	.005	<.001	3	4
BRCA	NUDT12 →	+0.624	+0.658	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,926 associations by consensus.

Exploration

SLC22A4 survival (RNA) · tumor vs normal (RNA) · all SLC22A4 data types