Across TCGA patient cohorts, SLC22A25 mutation is significantly associated with the RNA expression of many other genes, with 1,516 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC22A25-associated genes across cancer lineages are DDX11, OR2T2, and RNU6ATAC9P. Each is linked with SLC22A25 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC22A25-to-partner and partner-to-SLC22A25 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC22A25→partner) and Y-score (partner→SLC22A25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	DDX11 →	+0.520	+2.119	<.001	<.001	3	3
LUAD	OR2T2 →	+0.064	+4.526	<.001	.004	3	3
BLCA	RNU6ATAC9P →	+0.425	+3.878	<.001	.002	3	3
UCEC	NIPAL2 →	-0.522	-2.415	.001	.003	3	3
UCEC	FAF1 →	+0.304	+2.016	.003	.005	3	3
SKCM	RNA5SP209 →	+0.108	+1.582	.001	.006	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,516 associations by consensus.

Exploration

SLC22A25 survival (RNA) · tumor vs normal (RNA) · all SLC22A25 data types