SLC22A25

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SLC22A25 mutation is significantly associated with the total protein of many other genes, with 39 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC22A25-associated genes across cancer lineages are AR, MIG-6, and XRCC1. Each is linked with SLC22A25 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC22A25-to-partner and partner-to-SLC22A25 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC22A25→partner) and Y-score (partner→SLC22A25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECAR →-0.324-1.584.027.03633
LUSCMIG-6 →+0.142+2.816.029.03632
LUSCXRCC1 →+0.187+2.816.036.03632
UCECeIF4G →+0.274+2.000.024.01032
UCECINPP4B →-0.272-3.169.032.01832
UCECJNK_pT183_Y185 →-0.133-3.584.044.00232
Each partner links to its Q-omics profile. Showing the 6 strongest of 39 associations by consensus.

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