SLC22A18

Across TCGA patient cohorts, SLC22A18 mutation is significantly associated with the RNA expression of many other genes, with 2,116 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC22A18-associated genes across cancer lineages are RNU1-17P, PRAMEF12, and OR4X2. Each is linked with SLC22A18 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC22A18-to-partner and partner-to-SLC22A18 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU1-17P grouped by SLC22A18-low versus SLC22A18-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC22A18→partner) and Y-score (partner→SLC22A18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU1-17P →	+0.269	+2.743	<.001	<.001	3	2
UCEC	PRAMEF12 →	+0.406	+1.703	<.001	.005	3	2
COAD	OR4X2 →	+0.054	+7.741	<.001	.009	3	2
UCEC	FDX1P2 →	+0.119	+2.608	<.001	<.001	3	2
UCEC	RNA5SP418 →	+0.677	+1.956	<.001	.003	3	2
LIHC	MIR3666 →	+0.346	+5.268	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,116 associations by consensus.

RNU1-17P by SLC22A18 expression — UCEC

Explore this box plot interactively →