SLC22A14

Across TCGA patient cohorts, SLC22A14 mutation is significantly associated with the RNA expression of many other genes, with 1,752 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC22A14-associated genes across cancer lineages are RNU6-598P, ARAFP1, and RN7SL468P. Each is linked with SLC22A14 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC22A14-to-partner and partner-to-SLC22A14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-598P grouped by SLC22A14-low versus SLC22A14-high in READ.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC22A14→partner) and Y-score (partner→SLC22A14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	RNU6-598P →	+0.617	+5.039	<.001	.008	3	2
READ	ARAFP1 →	+0.071	+5.039	.003	.008	3	2
BRCA	RN7SL468P →	+0.419	+4.683	<.001	.007	3	2
BLCA	LINC02155 →	+0.060	+4.722	<.001	.003	3	2
SKCM	MIR6882 →	+0.136	+2.144	<.001	.005	3	2
LUAD	NOTCH2P1 →	+1.064	+4.612	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,752 associations by consensus.

RNU6-598P by SLC22A14 expression — READ

Explore this box plot interactively →