SLC22A14

Across TCGA cell cohorts, SLC22A14 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,288 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC22A14-associated GO terms across cancer lineages are Maintenance of protein localization in organelle, Establishment of protein localization to membrane, and Regulation of nucleocytoplasmic transport. Each is linked with SLC22A14 in more than 9 cancer types. Because this analysis shows association rather than direction, both SLC22A14-to-partner and partner-to-SLC22A14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Maintenance of protein localization in organelle grouped by SLC22A14-low versus SLC22A14-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC22A14→partner) and Y-score (partner→SLC22A14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Maintenance of protein localization in organelle →	+0.092	+0.164	.001	.003	3	10
SKIN	Establishment of protein localization to membrane →	+0.034	+0.135	.002	.003	3	10
PANCREAS	Regulation of nucleocytoplasmic transport →	+0.067	+0.265	.001	.007	3	10
SOFT_TISSUE	Viral process →	+0.066	+0.160	.001	.004	3	9
BREAST	Maintenance of location in cell →	+0.074	+0.203	<.001	.001	3	9
LUNG_NSCLC_LUSC	Response to heat →	+0.082	+0.208	<.001	.005	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,288 associations by consensus.

Maintenance of protein localization in organelle by SLC22A14 expression — BREAST

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