SLC22A14

Across TCGA cell cohorts, SLC22A14 mutation is significantly associated with the RNA expression of many other genes, with 465 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC22A14-associated genes across cancer lineages are GML, NEUROD4, and TEX101. Each is linked with SLC22A14 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC22A14-to-partner and partner-to-SLC22A14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GML grouped by SLC22A14-low versus SLC22A14-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC22A14→partner) and Y-score (partner→SLC22A14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	GML →	+0.078	+4.152	<.001	.009	3	1
BLOOD_Leukemia	NEUROD4 →	+0.058	+4.276	<.001	.007	3	1
BLOOD_Leukemia	TEX101 →	+0.303	+4.276	<.001	.007	3	1
BLOOD_Leukemia	GPR26 →	+0.057	+4.539	<.001	.007	3	1
BLOOD_Leukemia	OR2T12 →	+0.025	+4.705	<.001	.003	3	1
BLOOD_Leukemia	OR10Q1 →	+0.024	+4.969	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 465 associations by consensus.

GML by SLC22A14 expression — BLOOD_Leukemia

Explore this box plot interactively →