Across TCGA patient cohorts, SLC22A10 mutation is significantly associated with the total protein of many other genes, with 29 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC22A10-associated genes across cancer lineages are MEK1, ASNS, and Bcl-2. Each is linked with SLC22A10 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC22A10-to-partner and partner-to-SLC22A10 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC22A10→partner) and Y-score (partner→SLC22A10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MEK1 →	+0.331	+2.115	.012	.016	3	3
UCEC	ASNS →	+0.382	+2.000	.003	.030	3	2
UCEC	Bcl-2 →	-0.296	-1.874	.017	.049	3	2
UCEC	Caveolin-1 →	-0.604	-2.584	.020	.010	3	2
UCEC	cIAP →	+0.098	+2.710	.046	.003	3	2
UCEC	eIF4E →	+0.162	+2.321	.033	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 29 associations by consensus.

Exploration

SLC22A10 survival (RNA) · tumor vs normal (RNA) · all SLC22A10 data types