Across TCGA cell cohorts, SLC22A10 mutation is significantly associated with the RNA expression of many other genes, with 23 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC22A10-associated genes across cancer lineages are USP17L11, SRRM4, and CYP39A1. Each is linked with SLC22A10 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC22A10-to-partner and partner-to-SLC22A10 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC22A10→partner) and Y-score (partner→SLC22A10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	USP17L11 →	+0.077	+3.734	<.001	.006	3	2
BLOOD_Leukemia	SRRM4 →	+0.014	+4.060	<.001	.003	3	1
BLOOD_Leukemia	CYP39A1 →	+0.148	+3.769	<.001	.008	3	1
BLOOD_Leukemia	PDHA2 →	+0.009	+5.124	.009	<.001	3	1
BLOOD_Leukemia	DIRAS2 →	+0.082	+4.087	<.001	.009	3	1
BLOOD_Leukemia	INSM2 →	+0.216	+3.769	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

Exploration

SLC22A10 survival (RNA) · tumor vs normal (RNA) · all SLC22A10 data types