SLC22A1

Across TCGA cell cohorts, SLC22A1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,209 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SLC22A1-associated GO terms across cancer lineages are Pyrimidine-containing compound transmembrane transport, Metanephric proximal tubule development, and Thiamine transmembrane transport. Each is linked with SLC22A1 in more than 12 cancer types. Because this analysis shows association rather than direction, both SLC22A1-to-partner and partner-to-SLC22A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Pyrimidine-containing compound transmembrane transport grouped by SLC22A1-low versus SLC22A1-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC22A1→partner) and Y-score (partner→SLC22A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Pyrimidine-containing compound transmembrane transport →	-0.111	-0.424	.001	.002	3	13
PANCREAS	Metanephric proximal tubule development →	-0.215	-0.411	.001	.005	2	12
CNS	Thiamine transmembrane transport →	-0.837	-0.302	<.001	.006	3	9
URINARY_TRACT	Putrescine transport →	-0.232	-0.565	.001	.006	3	8
LARGE_INTESTINE	Protein targeting →	+0.033	+0.399	.001	<.001	3	8
SOFT_TISSUE	Protein localization to lysosome →	+0.046	+0.355	.009	.009	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,209 associations by consensus.

Pyrimidine-containing compound transmembrane transport by SLC22A1 expression — STOMACH

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