SLC20A2

Across TCGA cell cohorts, SLC20A2 mutation is significantly associated with the RNA expression of many other genes, with 76 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC20A2-associated genes across cancer lineages are FAM47B, PTH, and SCGB2A1. Each is linked with SLC20A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC20A2-to-partner and partner-to-SLC20A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FAM47B grouped by SLC20A2-low versus SLC20A2-high in BONE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC20A2→partner) and Y-score (partner→SLC20A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	FAM47B →	+0.030	+5.169	<.001	.004	3	2
LUNG_NSCLC_LUAD	PTH →	+0.045	+4.887	<.001	.009	3	2
BONE	SCGB2A1 →	+0.076	+5.169	<.001	.004	3	1
BONE	KRT71 →	+0.203	+5.169	<.001	.004	3	1
BONE	OR6C2 →	+0.219	+5.169	<.001	.004	3	1
BONE	GPR139 →	+0.023	+5.169	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 76 associations by consensus.

FAM47B by SLC20A2 expression — BONE

Explore this box plot interactively →