SLC1A3

Across TCGA patient cohorts, SLC1A3 mutation is significantly associated with the RNA expression of many other genes, with 3,507 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC1A3-associated genes across cancer lineages are RN7SL278P, YWHAEP5, and NCAPH2. Each is linked with SLC1A3 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC1A3-to-partner and partner-to-SLC1A3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL278P grouped by SLC1A3-low versus SLC1A3-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC1A3→partner) and Y-score (partner→SLC1A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RN7SL278P →	+0.187	+2.813	<.001	<.001	3	3
UCEC	YWHAEP5 →	+0.358	+2.254	.008	.005	3	3
UCEC	NCAPH2 →	+0.483	+2.392	<.001	<.001	3	3
UCEC	RAD51 →	+0.797	+2.885	<.001	<.001	3	3
LIHC	RN7SKP42 →	+0.154	+6.008	<.001	.002	3	2
LIHC	VDAC2P4 →	+0.063	+5.544	.007	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,507 associations by consensus.

RN7SL278P by SLC1A3 expression — SKCM

Explore this box plot interactively →